CBD dose is based on milligrams per pound of dog’s body weight. If your dog has never had CBD start with 0.05mg per #, twice a day. Mild dose 0.125mg per #, twice a day, Moderate dose 0.25mg per#, twice a day, High Dose 0.5mg per# twice a day.Make sure you treat it like any other supplement and store it out of reach of children and pets.